Retinal thickness measurements with optical coherence tomography and the scanning retinal thickness analyzer.

PURPOSE To assess the reproducibility of retinal thickness measurements in normal subjects and to compare foveal thickness using optical coherence tomography (OCT) and the scanning retinal thickness analyzer (RTA). METHODS Two examiners performed foveal thickness measurements in 24 eyes of 12 healthy subjects using both OCT and the scanning RTA. Intraclass correlation coefficients (ICC) (intra-examiner and inter-examiner) were calculated for the paired foveal thickness measurements obtained with each instrument. RESULTS The average foveal thicknesses measured with OCT and the scanning RTA were 155.1 +/- 14.9 microm and 107.8 +/- 18.6 microm, respectively. The intra-examiner ICCs from the two sessions using the OCT and the scanning RTA were 0.99 and 0.78 and 0.89 and 0.99, respectively. The inter-examiner ICCs of the OCT and the scanning RTA were 0.99 and 0.99, respectively. There was a significant correlation between the foveal thickness measurements with these two instruments (R2 = 0.629, P < 0.0001). CONCLUSION The foveal thicknesses measured using OCT and the scanning RTA in healthy subjects agreed with the previously reported data on foveal thickness. Both instruments can reproducibly quantitate foveal thickness.